IGF1 LR3 – 1mg

IGF1-LR3

Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic peptide and lengthened analogue of eukaryotic insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence (“arginine 3”), and also has an additional 13 amino acids at its N-terminus. As a result, it is approximately three times more bioactive than IGF-1, and possesses a significantly longer half-life of about 20-30 hours (relative to IGF-1’s half-life of about 12-15 hours). Research use only. Not intended for human consumption. These statements have not been evaluated by the FDA and this research compound is in no way intended to treat, diagnose or prevent any disease or condition. To view lab reports in detail, please click on the product image, then scroll to the right to see our 3rd party independent chromatography results in the large image viewing carousel. Item Quantity Discounts in the table on this page are stackable with the Cart Subtotal Discount codes shown in the header above (and on the Cart Page) to increase your savings!

MF: C71H119N17O19S

MW: 1546.9g/mol

References:

1.) PubChem. “PubChem.” Pubchem.ncbi.nlm.nih.gov, pubchem.ncbi.nlm.nih.gov/#query=%22Insulin-like%20growth%20factor%20I%20(57-70)%22. Accessed 13 May 2024.

2.) White, Alicia, et al. “Attenuated Glucose-Stimulated Insulin Secretion during an Acute IGF-1 LR3 Infusion into Fetal Sheep Does Not Persist in Isolated Islets.” Journal of Developmental Origins of Health and Disease, vol. 14, no. 3, 1 June 2023, pp. 353–361, www.cambridge.org/core/journals/journal-of-developmental-origins-of-health-and-disease/article/abs/attenuated-glucosestimulated-insulin-secretion-during-an-acute-igf1-lr3-infusion-into-fetal-sheep-does-not-persist-in-isolated-islets/D5FC9F9289BF85DCE5EF4F9BBD5A9901, https://doi.org/10.1017/S2040174423000090. Accessed 13 May 2024.

3.) Prelle, Katja, et al. “Insulin-like Growth Factor I (IGF-I) and Long R3IGF-I Differently Affect Development and Messenger Ribonucleic Acid Abundance for IGF-Binding Proteins and Type I IGF Receptors in in Vitro Produced Bovine Embryos*.” Endocrinology, vol. 142, no. 3, 1 Mar. 2001, pp. 1309–1316, https://doi.org/10.1210/endo.142.3.8038. Accessed 19 Oct. 2023.